Yes. According to the Centers for Disease Control and Prevention (CDC), the COVID-19 vaccines offer protection against infection by most variants. Most important, they have prevented serious illness, hospitalization, and death, even at a time when new variants are spreading around the world.
In September 2022, updated booster vaccines became available. These new boosters contain an updated bivalent formula that both boosts immunity against the original coronavirus strain and also protects against the newer Omicron variants that account for most of the current cases. Updated boosters are intended to provide optimal protection against the virus and address waning vaccine effectiveness over time.